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TREATMENT EMERGENT CENTRAL SLEEP APNEA IN PATIENTS TREATED WITH CPAP AND BIPAP FOR OSA

      TOPIC: Sleep Disorders
      TYPE: Original Investigations
      PURPOSE: 1.To study the outcomes of PAP therapy in patients developing Complex apnea after starting the treatment of OSA2.To study the effectiveness of BiPAP vs CPAP in patients developing complex sleep apnea post initiation of PAP therapy for OSA
      METHODS: We followed up 25 patients who were treated with CPAP and BiPAP each for severe OSA and had developed Central sleep apnea post initiation of therapy. We repeated PSG in these patients after approximately 7-8 months of initiation of PAP therapy.
      RESULTS: 1.95% of our study population was men2.Mean age was 64±7.73.Mean BMI of study population was 35.1±6.24.AHI of our study population at the initiation of therapy was 68.9±24.25.6 months after initiation of CPAP therapy 45.9% of patients had a residual AHI<15, whereas only 8% had residual AHI>15.6.6 months after initiation of BiPAP therapy 72.9% of patients had a residual AHI<10, whereas only 8% had residual AHI>15.8.There was further resolution of complex sleep apnea observed after 6 months of BiPAP therapy with 22 patients treated with BiPAP completed recovered from complex sleep apnea and 18 patients treated with CPAP recovered from complex sleep apnea after 6 months of therapy7.Changes in initial CPAP and BiPAP pressure settings were not found to be significantly related to residual AHI improvement.
      CONCLUSIONS: Less incidence and better improvement in treatment emergent central sleep apnea was thus observed after 6 months of BiPAP therapy.
      CLINICAL IMPLICATIONS: Changes in initial CPAP pressure settings are not associated with improved residual AHI
      DISCLOSURES: No relevant relationships by Sarang Patil, source=Web Response