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EVALUATION OF PATIENTS WITH COVID-19 RECEIVING LONG-TERM OXYGEN SUPPORT IN POST-COVID PERIOD

      TOPIC: Respiratory Care
      TYPE: Original Investigations
      PURPOSE: COVID-19 can lead to hypoxemia as a result of damage due to inflammatory responses to SARS-CoV-2 in the respiratory system. Persistent post-COVID syndrome, may involve persistent physical and medical sequelae following COVID-19, including chronic hypoxemia. Long-term oxygen therapy (LTOT) is an established treatment for patients with chronic hypoxemia, generally used in chronic airway diseases. We aimed to evaluate COVID-19 patients using LTOT in post-COVID period and assess whether the need for oxygen support continues.
      METHODS: This cross-sectional, multicentered study included 320 COVID-19 patients who were questioned about LTOT at the control visit. Patients' demographics, admission symptoms, laboratory and radiological findings were recorded retrospectively from hospital database.
      RESULTS: There were 189 men (59.1%) and 131 women (40.9%) with the mean age of 70.6±12.6. Average visit time for evaluation was 2.03±1.39 months. It was learned that 15% of the patients died during the post-COVID process, which was related with high age (p=0.003), usage of mechanical ventilation (p=0.019) and no steroid administration (p=0.048) during hospitalization. The need for oxygen support continued in 22.9% of the patients. Admission to intensive care unit and having a high serum D-dimer level (> 1000 μg/L) were significant risk factors for the ongoing need of home oxygen support (p= 0.026 and 0.010, respectively). The oxygen saturation level at hospital admission was found to be significantly lower in patients who continued to require oxygen therapy (p<0.001).
      CONCLUSIONS: The fact that most COVID-19 patients do not need LTOT in the post-COVID period indicates that the clinicians should be more selective when planning home oxygen therapy. Due to the high mortality rate and variable oxygen demand during the post-COVID process, control visits of patients should be done more frequently.
      CLINICAL IMPLICATIONS: For this patient group, instead of more permanent devices such as an oxygen concentrator, devices that can be used temporarily such as an oxygen tanks may be preferred.
      DISCLOSURES: no disclosure on file for Pınar Akın Kabalak;
      No relevant relationships by SAHINUR AYCAN ALKAN, source=Web Response
      No relevant relationships by Ersin ALKILINC, source=Web Response
      no disclosure on file for Ayşegül Altıntop Geçkil;
      no disclosure on file for sertaç arslan;
      no disclosure on file for Yusuf Aydemir;
      no disclosure on file for Ozgur Batum;
      No relevant relationships by Hüsnü Baykal, source=Web Response
      No relevant relationships by Fulsen Bozkus, source=Web Response
      no disclosure on file for Aylin Capraz;
      no disclosure on file for Julide Celdir Emre;
      No relevant relationships by Arzu Mirici, source=Web Response
      No relevant relationships by Aysun Sengul, source=Web Response
      No relevant relationships by Yasemin Söyler, source=Web Response
      no disclosure on file for sule tas gulen;
      no disclosure on file for pakize ayse turan;
      No relevant relationships by Muzaffer Onur Turan, source=Web Response
      No relevant relationships by Onur Yazici, source=Web Response
      no disclosure on file for pinar yildiz;