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SEVERE BRONCHIAL ASTHMA OR UNCONTROLLED COURSE OF THE DISEASE

      TYPE: Abstract Publication
      TOPIC: Allergy and Airway
      PURPOSE: Determination of incidence of true severe bronchial asthma among patients with uncontrolled course.
      METHODS: There were included patients with severe bronchial asthma (n = 54). Median age 56 [49.25; 62] years, median duration of the disease 14 [5; 21] years. Patients were assessed during hospitalization for the history of life and disease, and the frequency and causes of asthma exacerbations were analyzed. The volume of basic therapy that patients received during 12 months before admission to hospital, including the regularity of its use, was estimated. The assessment of commitment to therapy was studied using a validated Moriski-Green questionnaire.
      RESULTS: In patients with severe asthma irregular intake of basic therapy is registered in 25.9%, inadequate anti-inflammatory therapy - in 9.6%, absence of therapy - in 7.4% of cases. According to the results of anonymous questionnaire with the help of Moriski-Green questionnaire, low commitment to basic therapy is registered in 68.5% of patients, low motivation in 29.6% of patients and low awareness in 31.5% of respondents. Evaluation of the inhalation technique revealed that more than 50% of patients suffering from asthma did not perform the inhalation technique correctly through both the metered-dose aerosol inhaler and the powder inhaler.
      CONCLUSIONS: Insufficient and irregular therapy of the disease, errors in the inhalation technique, the presence of concomitant "untreated" pathology can mislead the attending doctor and give a false picture of asthma of a heavy course.
      CLINICAL IMPLICATIONS: Low adherence to prescribed treatment is one of the main reasons for poor control, poor quality of life for patients and high risk of exacerbation.
      DISCLOSURE: No significant relationships.
      KEYWORDS: Severe asthma, phenotype of asthma, Uncontrolled asthma