The Pulmonary Response to Fiberglass Dust

Report of the Committee on Environmental Health
  • American College of Chest Physicians
      Pneumoconiosis has recently been redefined by the International Labour Organization to be the accumulation of dust in the lungs and the tissue reaction to its presence. In terms of this definition, even the inhalation of soot by city dwellers leads to pneumoconiosis. The pulmonary response to the presence of fiberglass particles is similar to that following the inhalation of soot, namely, a macrophagic reaction.
      • Gross P
      • Kaschak M
      • Tolker EB
      • et al.
      The pulmonary reaction to high concentrations of fibrous glass dust: A preliminary report.
      To read this article in full you will need to make a payment
      Subscribe to CHEST
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Gross P
        • Kaschak M
        • Tolker EB
        • et al.
        The pulmonary reaction to high concentrations of fibrous glass dust: A preliminary report.
        Arch Environ Health. 1970; 20: 696-704
        • Schepers GWH
        • Durkan TM
        • Delahant AB
        • et al.
        The biological action of Fiberglas-plastic dust.
        Arch Ind Health. 1958; 18: 34-57
        • Schepers GWH
        Pulmonary histologic reactions to inhaled Fiberglas-plastic dust.
        Am J Path. 1959; 35: 1169-1187
        • Gross P
        • Harley RA
        • Davis JMG
        The effects of fibrous glass dust on the lungs of animals.
        in: Transcript of Proceedings of the Symposium on Occupational Exposure to Fibrous Glass. vol 2. University of Maryland, College Park, Md1974: 31-38
        • Wagner JC
        • Berry G
        • Timbrell V
        Mesotheliomata in rats after inoculation with asbestos and other materials.
        Br J Cancer. 1973; 28: 173-185
        • Grasso P
        • Golberg L
        Subcutaneous sarcoma as an index of carcinogenic potency.
        Food Cosmet Toxicol. 1966; 4: 297-320
        • Milby TH
        • Wolf CR
        Respiratory tract irritation from fibrous glass inhalation.
        J Occup Med. 1969; 11: 409-410
        • Bjure J
        • Soderholm B
        • Widimsky J
        Cardiopulmonary function studies in workers dealing with asbestos and glass wool.
        Thorax. 1964; 19: 22-27
        • Wright GW
        Airborne fibrous glass particles.
        Arch Environ Health. 1968; 16: 175-181
        • Nasr ANM
        • Ditchek T
        • Scholtens PA
        The prevalence of radiographic abnormalities in the chest of fiber glass workers.
        J Occup Med. 1971; 13: 371-376
        • Utidjian HMD
        • de Treville RTP
        Fibrous glass manufacturing and health; Report of an epidemiological study.
        in: Proceedings of the 35th Annual Meeting of the Industrial Health Foundation. Industrial Health Foundation, Pittsburgh1970: 1-9
        • de Treville RTP
        • Hook HL
        • Morrice Jr., G
        Fibrous glass manufacturing and health: Results of a comprehensive physiological study.
        in: Proceedings of the the 35th Annual Meeting of the Industrial Health Foundation. Industrial Health Foundation, Pittsburgh1970: 10-18
        • Hill JW
        Glass fibres: Absence of pulmonary hazard in production workers.
        Br J Ind Med. 1973; 30: 174-179
        • Hill JW
        The epidemiology of glass fibre exposure and a critique of its significance.
        in: Transcript of Proceedings of the Symposium on Occupational Exposure to Fibrous Glass. vol 2. University of Maryland, College Park, Md1974: 139-147
        • Bayliss D
        Mortality patterns among fibrous glass production workers: Provisional report.
        in: Transcript of Proceedings of the Symposium on Occupational Exposure to Fibrous Glass (vol 2). University of Maryland, College Park, Md1974: 175-183
        • Enterline PE
        • Henderson V
        The health of retired fibrous glass workers.
        Arch Environ Health. 1975; 30: 113-116
        • Gross P
        • Harley RA
        • Davis JMG
        The lungs of fiber glass workers: Comparison with the lungs of a control population.
        in: Transcript of Proceedings of the Symposium on Occupational Exposure to Fibrous Glass. vol 2. University of Maryland, College Park, Md1974: 147-157
        • Gross P
        • Davis JMG
        • Harley RA
        Lymphatic transport of fibrous dust from the lungs.
        J Occup Med. 1973; 15: 186-189
        • Gross P
        • Harley RA
        • Davis JMG
        • et al.
        Mineral fiber content of human lungs.
        Am Ind Hyg Assoc J. 1974; 35: 148-151
      1. Threshold Limit Values for Chemical Substances and Physical Agents in the Workroom Environment with Intended Changes for 1973. American Conference of Governmental Industrial Hygienists, Cincinnati1973

      Uncited Reference

        • Schepers GWH
        The biological action of glass wool.
        Arch Ind Health. 1955; 12: 280-287
        • Schepers GWH
        • Delahant AB
        An experimental study of the effects of glass wool on animal lungs.
        Arch Ind Health. 1955; 12: 276-279
        • Kushner M
        The effects of intratracheal instillation of glass fibers of varying size in guinea pigs.
        in: Transcript of Proceedings of the Symposium on Occupational Exposure to Fibrous Glass. vol 2. University of Maryland, College Park, Md1974: 20-31
        • Stanton MF
        • Wrench C
        Mechanisms of mesothelioma induction with asbestos and fibrous glass.
        J Nat Cancer Inst. 1972; 48: 797-821
        • Maroudas NG
        • O'Neill CH
        • Stanton MF
        Fibroblast anchorage in carcinogenesis by fibres.
        Lancet. 1973; 1: 807-809
        • Pott F
        • Friedrichs KH
        Tumoren der Ratte nach i.p.-Injektion faserförmiger Stäube.
        Naturwissenschaften. 1972; 59: 318
        • Huth F
        Results of animal carcinogenesis studies after application of fibrous glass and their implications regarding human exposure.
        in: Transcript of Proceedings of the Symposium on Occupation Exposure to Fibrous Glass. vol 2. University of Maryland, College Park, Md1974: 45-55
        • Bisehoff F
        • Bryson G
        Carcinogenesis through solid state surfaces.
        in: Homburger F Progress in Experimental Tumor Research. vol 5. S Karger AG, Basel1964: 85-97
        • Timbrell V
        • Pooley F
        • Wagner JC
        Characteristics of respirable asbestos fibers.
        in: Proceedings of the International Conference on Pneumoconiosis, Johannesburg, 1969. Oxford University Press, London1970: 3
        • Murphy GB
        Fiber glass pneumoconiosis.
        Arch Environ Health. 1961; 3: 102-108
        • Dement JM
        Preliminary results of the NIOSH industry-wide study of the fibrous glass industry.
        in: Transactions of the 35th Annual Meeting of the American Conference of Governmental Industrial Hygienists. American Conference of Governmental Industrial Hygienists, Cincinnati1973: 69-74

      Linked Article