Medication Adherence Patterns in Chronic Obstructive Pulmonary Disease

      While medical treatment of COPD has advanced, the failure to adhere to regimens for medication poses a significant barrier to effective management. Furthermore, no data are available regarding adherence for patients within the United States. Data from this investigation indicate that 78 outpatients from a medical center in the southeastern region of the United States were prescribed an average of 6.26 medications with both various dosing schedules and different modes of administration. Adherence was poor, with 42 patients (54 percent) underutilizing medications, 39 patients (50 percent) overutilizing medications during periods of respiratory distress, and 24 patients (31 percent) employing ineffective inhaler dosing techniques. Prescription patterns and adherence were not associated with demographic variables; however, adherence was related to classes of medication and situational variables.
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        • Kaplan RM
        • Toshima MT
        • Atkins CJ
        • Ries RL
        Behavioral interventions for patients with COPD.
        in: O'Keene JK Shumaker SA Adoption and maintenance of behavior for optimal health. Springer-Verlag, New York1990
        • Windsor RA
        • Green LW
        • Roseman JM
        Health promotion and maintenance for patients with chronic obstructive pulmonary disease: a review.
        J Chronic Dis. 1980; 33: 5-12
        • Taylor DR
        • Kinney CD
        • McDevitt DG
        Patient compliance with oral theophylline therapy.
        Br J Clin Pharm. 1984; 17: 15-20
        • Chryssidis E
        • Frewin DB
        • Frith PA
        • Dawes ER
        Compliance with aerosol therapy in COPD.
        NZ Med J. 1981; 250: 375-377
        • James PNE
        • Anderson JB
        • Prior JG
        • White JP
        • Henry JA
        • Cochrane GM
        Patterns of drug taking in patients with chronic airflow obstruction.
        Postgrad Med J. 1985; 61: 7-10
        • Moriskey D
        • Green L
        • Levine D
        Concurrent and predictive validity of a self reported measure of medication adherence.
        Med Care. 1986; 24: 67-74
        • Brooks CM
        • Soong S
        • Martin B
        • Stewart L
        Assessing self management skills of adults with asthma. Read before the annual meeting of the American Psychological Association, New York1987
        • McFadden ER
        Inhaled aerosol bronchodilators. Williams and Wilkins, Baltimore1986
        • Manzella B
        • Brooks M
        • Richards J
        • Windsor R
        • Soong S
        • Bailey W
        Assessing the use of metered dose inhalers by adults with asthma.
        J Asthma. 1989; 26: 223-230
        • Cronbach LJ
        • Gleser GC
        • Nanda H
        • Rajaratnam N
        The dependability of behavioral measurements: the theory of generahzability for scores and profiles. John Wiley and Sons, Inc, New York1972
        • Hensen M
        • Bellack AS
        Behavioral assessment: a practical handbook. Pergamon Press, New York1976